BROWSE CASE STUDIES Case Studies > Factors Associated With Opioid Overdose After an Initial Opioid Prescription

Factors Associated With Opioid Overdose After an Initial Opioid Prescription

January 2022

CATEGORIES:

Consumers, Providers, Researchers, Population Health

FILTERS:

Utilization, Quality, Health, Pharmacy, Commercial, Medicaid

CONTACT

Scott Weiner
sweiner@bwh.harvard.edu

Because the opioid epidemic continues to be a public health crisis in the US, investigators aimed to asses the patient and prescription-related factors associated with opioid-related overdose.

Scott Weiner, MD, MPH, Department of Emergency Medicine, Brigham and Women's Hospital, led a team of investigators in conducting a cohort study that evaluated opioid-naive adult patients.

The main outcome was an overdose event with a follow-up to identify the fatality of the opioid overdose. The primary risk factors included being 75 years or older, being male, receiving Medicaid or Medicare Advantage coverage, having a comorbid substance use disorder or depression, and having medical comorbidities.